9 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... fluid overload, PCC ... #hematology #oncology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Signs and Symptoms ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... changes • Urinary symptoms ... dysfunction • PSC ... appendages • FMF ... Chronic #Causes #Differential
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... nausea, vomiting, abdominal ... infiltration) Differential ... Diagnosis: Viral
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
CNS symptoms (headache ... Behcet disease) Differential ... • Nonsurgical abdominal ... management #signs #symptoms ... #rheumatology #
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
CT abdomen if abdominal ... full infectious work-up ... days → add fungal work-up ... syndrome): - Hematologic ... Oncology #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis

EPIDEMIOLOGY:
PFAPA is the most common syndrome entailing
) PATHOPHYSIOLOGY ... , including abdominal ... DIFFERENTIAL DIAGNOSIS ... The diagnosis of ... #Fever #Diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Diagnosis Framework ... Aldolase levels • EMG ... Other Diseases: • PBC ... #differential #