7 results
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... Alcoholic Hepatitis (AH ... >1.5, and both values ... gastrointestinal bleed, hypotension ... #hepatology #criteria
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH ... #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... Viral Infection Clinical ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... matter, spinal cord ... Behcet syndrome (Clinical ... ) Differential Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... appreciate the value ... bacteremia and hypotension ... neutrophil #WBC #CBC #hematology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... Pathophysiology: • Portal hypertension ... Diagnosis (Clinical ... • Urine sodium could ... Hepatorenal #Syndrome #Hepatology