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diagnosis algorithm management rheumatology classification hepatology secondary systemic cll dermatology gastroenterology generalized hodgkins lymphocytic lymphoma pruritus pulmonary thrombocytosis workup abdominal
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Myelogenous Leukemia ... : • Acute or Chronic ... disorders • Celiac disease
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Lymphadenopathy - Differential ... Age > 50 • Chronic ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... Myelofibrosis (MF ... leukemia (CML) ... #hematology #secondary
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Disorders: • Chronic ... Colitis and Crohn’s Disease ... #Diagnosis #causes ... #hematology #basophils
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Cholestatic liver disease ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... #generalized #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... extramedullary disease ... -> AML: Blast crises ... #Hematology #Oncology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... infarction • Lymphoma/Leukemia ... appendages • FMF ... #Causes #Differential
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... cyst, Caroli's disease ... Inflammatory: Chronic ... pancreatitis, PSC ... diagnosis #hepatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... cells can indicate disease ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... involved) • No leukemic ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
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