40 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... discoloration) • Liver ... #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... • Cholestatic liver ... disease Creatinine ... renal failure/uremia ... Diagnosis #Algorithm
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... Signs and Symptoms ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... erythematosus #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... - Hemolytic anemia ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... Classification #Diagnosis ... #Differential #
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... >10 mmHg - clinically ... #Diagnosis #causes ... #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... with leukopenia, anemia ... thrombocytopenia • Liver ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
diagnosis; however ... assessed for Lyme disease ... rashes but without signs ... pathognomonic for SJS or EM ... #Diagnosis #Dermatology