32 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Osteomyelitis / Septic Arthritis ... #Joint #Pain #SickleCell ... #Disease #differential ... diagnosis #causes #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... Disease: • Pain ... the subchondral bone ... #Pain #MSK #rheumatology ... approach #workup #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... Heberden's nodes (DIP joints ... #pain #differential ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis ... Differential Diagnosis ... Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... nonerosive inflammatory arthritis ... • Bone and joint ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Vascular Joint Pain ... - Differential ... • Sickle Cell Anemia ... Peripheral Vascular Disease ... Vascular #JointPain #MSK
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint ... pain/Night sweats ... - Aneurysmal bone ... #diagnosis #msk