13 results
Liver Mass Differential Diagnosis
Solid:
 • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 •
Liver Mass Differential ... • Malignant: HCC ... disease, Biliary ... #Mass #Differential ... #Diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Drugs - Primary biliary ... biliary diseases
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... hepatitis, Acute biliary ... Extrahepatic • Biliary ... #Injury #Differential ... Acute #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
Dilatation - Differential ... cyst, Caroli's disease ... pancreatitis, PSC ... #diagnosis #hepatology ... #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Extrahepatic - Biliary ... - Obstruction: Biliary ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
disease 6-9 mo ... Calculate R-Value ... Idiosyncratic #differential ... #algorithm #gastroenterology ... #hepatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... Endomyseal antibody (EMA ... diagnosis #table #rheumatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Cholestatic disease ... Bile Ducts • PSC ... Duct Stone • Biliary
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... #Diagnosis #hematology