11 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Hepatocellular ... • R value = (ALT ... Transaminitis #diagnosis ... #differential # ... hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Diagnosis Hepatocellular ... #Differential # ... Acute #algorithm #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Transaminitis Hepatocellular ... kwburak #LFTs #Elevated ... #hepatology #LiverFunctionTests
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Calculate R-Value ... • Hepatocellular ... Idiosyncratic #differential ... #Diagnosis #Management
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... specificity to elevated ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... specificity to elevated ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
- Typically hepatocellular ... pattern of liver injury ... reported (eg AIH-PBC ... IgG typically elevated ... #Management #Hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... - Prosthetic valves ... hepatitis • Acute Hepatocellular ... #differential #
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... 4, fibrosis-4; HCC ... , hepatocellular ... algorithm #Referral #Management ... #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if WBC > 5 or elevated ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... #management #hematology