49 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... • Cholestatic disease ... Bile Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... biliary Cholangitis (PBC ... - PSC - Other ... ALP #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
chronic kidney disease ... disorder - TSH, LFTs ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... , Drugs, Liver Disease ... #Diagnosis #hematology
Liver Mass Differential Diagnosis
Solid:
 • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules
 •
Liver Mass Differential ... • Malignant: HCC ... Polycystic liver disease ... #Liver #Mass #Differential ... #Diagnosis #hepatology
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver Disease ... Hepatocellular Carcinoma (HCC ... Complications #diagnosis #management ... #summary #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Syndrome, Celiac Disease ... , 1° PSC, Cystic ... Liver #Injury #Differential ... Acute #algorithm #hepatology