12 results
diagnosis algorithm hematology liver causes gastroenterology hemolysis hepatitis injury transaminitis aih apml autoimmune biliary chemistry cholangitis cirrhosis differentiation dili drug
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... Calculate R-Value ... • Hepatocellular ... Idiosyncratic #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Transaminitis Hepatocellular ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
HTR • Drug-induced ... AIHA - Abnormal ... Cold AIHA • PCH ... PNH • Drug-induced ... Prosthetic heart valves
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Cholestatic disease ... US — Normal Bile ... Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Thrombosis, Emboli Hepatocellular ... function may be abnormal ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... 4, fibrosis-4; HCC ... , hepatocellular ... algorithm #Referral #Management ... #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
but elevated as disease ... bile ducts Differential ... Sarcoidosis, Drug-induced ... , IgG4 related disease ... diagnosis #workup #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... - Typically hepatocellular ... reported (eg AIH-PBC ... upper limit of normal ... #Hepatology
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