11 results
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... staining on IF • No EM ... Glomerulonephritis #RPGN #Classification ... #Differential # ... Diagnosis #Nephrology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Diagnosis Framework ... Infectious: Influenza, EBV ... Resp/Heme: CHF, valves ... I am weak": • Myopathy ... #neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... PCR 50% sensitive ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... proximal weakness Myopathy ... electromyographic (EMG ... #Diagnosis #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
late-onset nemaline myopathy ... Scleromyxedema (CNS ... to cold IgG • Lupus ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... effect/Edema • EBV ... #Infections #differential ... InfectiousDiseases #Neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... and CNS • Headache ... Erythematosus #Diagnosis
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... Bacterial Meningitis - Differential ... virus • CMV • EBV ... Singh @rav7ks #CNS ... #diagnosis #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
lumbar spine • MCC ... equina syndrome (CES ... Diagnosis: • ... #diagnosis #causes ... #neurology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... the spinal cord (Myelopathy ... Brucellosis - Dengue, EBV ... #management #neurology ... #differential