11 results
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
treat non-renal SLE ... class V LN • MMF ... treat extra-renal SLE ... Algorithm #Treatment #management ... #nephrology
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... #SLE #Classification ... #Classes #differential ... #diagnosis #management ... #nephrology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Causes of Acute Kidney ... Interstitial nephritis ... Urethral stricture/valves ... Postrenal #Failure #Differential ... #Nephrology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
) - Loss of kidney ... nephropathy, lupus nephritis ... Glomerulonephritis #RPGN #Classification ... #Differential # ... Diagnosis #Nephrology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness - Differential ... Bacteremia, Sepsis • Kidneys ... Resp/Heme: CHF, valves ... body-), PMR, RA, SLE ... Diagnosis #causes #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Antiribosomal P, APLA, PAC ... C4) • ds-DNA: Kidney ... • Kidney biopsy
Hematuria in Post-Renal Transplant Patient
Prevalence up to 12% in the postrenal transplant patient
 • Bacterial: Escherichia
Goodpasture's syndrome, SLE ... Renal #Transplant #differential ... #diagnosis #kidney ... #blood #urine #management ... #treatment #nephrology
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Proliferative Lupus Nephritis ... Oral MMF 2-3 g/d ... Hydroxychloroquine Kidney ... Proliferative #Lupus #Nephritis ... #management #nephrology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... Serologic and EMG ... Gravis #diagnosis #management ... #neurology