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Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Gravis is an autoimmune ... life-threatening Differential ... Diagnosis - ... Serologic and EMG ... #Gravis #diagnosis
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Diagnosis Algorithm ... #Neurology #Differential ... #Causes
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Poliomyelitis, Guillain-Barre ... Eaton Syndrome, Myasthenia ... #Causes #differential ... #diagnosis #neurology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
- Differential ... Resp/Heme: CHF, valves ... NMJ disorder (Myasthenia ... Diagnosis #causes ... #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Summary • an autoimmune ... 50 years in men Diagnosis ... More likely to cause ... glucocorticoids - can cause ... #management #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Diagnosis: • ... Electrodiagnostic studies - EMG ... Barre #Syndrome #diagnosis ... management #treatment #neurology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Muscle Weakness ... neurologic disease • Myasthenia ... Myopathy #mimics #diagnosis ... #differential # ... causes #neurology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... Cold AIHA • Alloimmune ... Cold AIHA • PCH ... Prosthetic heart valves
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... Postsynaptic: Myasthenia ... necrotizing myopathy • Autoimmune ... Diagnosis #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... SinaiBmoreIMRes #GBS #Guillain ... #management #neurology
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