34 results
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Resp/Heme: CHF, valves ... Polyneuropathy, ALS ... NMJ disorder (Myasthenia ... Diagnosis #causes ... #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Diagnosis Algorithm ... #Neurology #Differential ... #Causes
Causes of Orthopnea - Differential Diagnosis Framework

 • Fear and Anxiety
 • Pleural Effusion
 • Ascites
- Differential ... • Ascites • COPD ... Diaphragmatic weakness ... lesion: ALS, MS ... #Diagnosis #Causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Cord: Demyelinating ... Motor Nerves: ALS ... Eaton Syndrome, Myasthenia ... #Causes #differential ... #diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... Diagnosis - ... Serologic and EMG ... precipitated by: Drugs, infection
Multiple Cranial Neuropathies - High Yield Differential Diagnosis
 • Intrinsic brainstem process
 • Compressive brainstem process
Diagnosis • Intrinsic ... Neurosarcoidosis • CNS ... important for facial weakness ... : • Myasthenia ... #Diagnosis #causes
Acute and Chronic Causes of Dyspnea - Differential Diagnosis
Pulmonary/Chest Wall:
 • Acute: Trauma, COPD exacerbation, Asthma
Acute and Chronic Causes ... , Anaphylaxis, Infection ... hernia, Obesity CNS ... Neuromuscular disease (eg myasthenia ... Encephalitis • Chronic: ALS
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... of the spinal cord ... Postsynaptic: Myasthenia ... Diagnosis #neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... lung nodules, may also ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Muscle Weakness ... neurologic disease • Myasthenia ... Sarcoidosis • Infections ... #differential # ... causes #neurology