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diagnosis neurology management syndrome barre gravis treatment algorithm amyotrophic autoimmune cauda caudaequina equina gbs generalized guillainbarre lateral myositis neuromuscular peripheral
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Motor Nerves: ALS ... Poliomyelitis, Guillain-Barre ... Mitochondrial myopathy ... #Causes #differential
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Neuropathy • Spinal ... • Congenital Myopathy ... #Neurology #Differential
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Resp/Heme: CHF, valves ... I am weak": • Myopathy ... Polyneuropathy, ALS ... NMJ disorder (Myasthenia ... Diagnosis #causes
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
crises”. ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... diagnosis #management #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... complete paralysis of all ... Electrodiagnostic studies - EMG ... of intrathecal spinal ... management #treatment #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
More likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... Sinai Hospital of ... diagnosis #management #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
• MCC- acute ... - Emergency Causes ... Tethered cord • Guillain-Barre ... lower extremity weakness ... #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Lesions of the spinal ... Postsynaptic: Myasthenia ... Myopathy: ... #Differential #
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... axonal • MRI - Spinal ... the intrathecal spinal ... SinaiBmoreIMRes #GBS #Guillain
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
brainstem and multiple spinal ... - Causes progressive ... EMG: LMN Signs in ... cervical and thoracic spine ... conditions listed in differential
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