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Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Neuropathy • Spinal ... • Congenital Myopathy ... #Neurology #Differential
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... neurologic disease • Myasthenia ... mimics #diagnosis #differential ... #causes #neurology
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Resp/Heme: CHF, valves ... I am weak": • Myopathy ... Polyneuropathy, ALS), NMJ disorder ... (Myasthenia, LEMS ... Diagnosis #causes
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Eaton Syndrome, Myasthenia ... Mitochondrial myopathy ... #Causes #differential
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... crises”. ... life-threatening Differential ... Serologic and EMG ... diagnosis #management #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... Lesions of the spinal ... Postsynaptic: Myasthenia ... Myopathy:
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... Cord Causes: 1 ... #diagnosis #neurology ... #differential
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
More likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... Sinai Hospital of ... diagnosis #management #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
cord (Myelopathy ... Weakness: - Weakness ... • Infectious causes ... diagnosis #management #neurology ... #differential
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
Causes of spinal ... • Extrinsic Causes ... - Radiation myelopathy ... syndromes #lesions #differential ... #diagnosis #neurology
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