26 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Limb- proximal weakness ... life-threatening Differential ... Serologic and EMG ... #diagnosis #management ... #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... Sensory Changes - Differential ... No Objective Weakness ... • Myasthenia Gravis ... #Neurology #Differential
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Syndrome, Myasthenia Gravis ... Neuromuscular #Weakness ... #Causes #differential ... #diagnosis #neurology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Proximal Muscle Weakness ... • Myasthenia gravis ... mimics #diagnosis #differential ... #causes #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness ... - Differential ... Resp/Heme: CHF, valves ... #Differential # ... Diagnosis #causes #neurology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... DIC, HELLP - Grafts ... , Valves, AS ... Drug-associated, PCH ... #Hemolysis #Differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia Gravis ... electromyographic (EMG ... #Differential # ... Diagnosis #neurology
Stroke Evaluation and Management Algorithm

Clinical suspicion of stroke (BE FAST)
 • Balance loss
 • Eyes: vision
Evaluation and Management ... asymmetry • Arm weakness ... Klaas #Stroke #Management ... Algorithm #diagnosis #differential ... #neurology #CVA
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... or respiratory weakness ... #Myasthenia #Gravis ... #diagnosis #management ... #neurology #treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
progressive flaccid weakness ... to a week • Weakness ... Electrodiagnostic studies - EMG ... Syndrome #diagnosis #management ... #treatment #neurology