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liver transaminitis acidosis acute alkaline alp chemistry cholestatic classification dili drug enzymes extravascular gastroenterology hematology hemolysis hepatitis hepatocellular idiosyncratic induced
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... • AST/ALT elevation ... • R value = (ALT ... #differential # ... hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... Intestine - Other causes ... Diagnosis #Algorithm ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Diagnosis Algorithm ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm ... #Causes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis #Causes ... #Acute #algorithm ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... #diagnosis #algorithm ... #hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... Prosthetic heart valves ... #Diagnosis #Algorithm ... #Causes #Hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... to bolus these values ... liver or renal injury ... #Differential # ... Diagnosis #causes
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