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lfts causes transaminitis hematology elevation function hemolysis hepatitis interpretation tests abnormal acidosis acute alkaline alp arterial chemistry classification druginduced elevated
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... Calculate R-Value ... #Liver #Injury # ... Idiosyncratic #differential ... gastroenterology #algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Algorithm DILI ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Diagnosis Framework ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... #Diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... diagnosis #algorithm ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... , Recreational Drugs ... #Injury #Differential ... #Acute #algorithm ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... 15X ULN - Drugs ... #diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Cholestasis - Drugs ... #Diagnosis #Algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... , PCH, Evans Syndrome ... , Liver Disease, ... #Diagnosis #hematology
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
Differential Diagnosis ... history (cardiac, liver ... renal disease), drug ... #EM #IM #Nephro ... #Algorithm #Ddxof
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