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diagnosis management oncology causes hemolysis acidosis acquired algorithm apml arteritis cap community differentiation elevation erythematosus extravascular gap gca giantcell globulin
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
• Sickle cell ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... Langerhans cell ... #Diagnosis #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... Imaging: CXR- pulmonary ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... very remarkable w/differential ... systemic complaints- anemia ... Treatment of GCA
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... to bolus these values ... output - Acute pulmonary ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Bands > 15% • Uremia ... negative predictive value ... procalcitonin level Treatment ... cultures/nasal PCR ... #Pulmonary #Community
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Growers (Runyon Classification ... Advanced HIV (CD4 cell ... Hematologic malignancy ... Bone Marrow - Anemia ... NTM #Infections #differential
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