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hemolysis causes algorithm anesthesia anesthesiology cardiacarrest classification elevation extravascular intraoperative intravascular lactate lactic management mds myelodysplasia myelodysplastic oncology schistocytes syndromes
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... microangiopathies (TMA) - TTP ... macroangiopathic hemolytic anemia ... Catastrophic APLS BCM IM ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... immune-complex hemolytic anemia ... • MAHA (TTP ... Prosthetic heart valves ... #Causes #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity - A low value ... If the value is ... WBC count and differential ... #Workup #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... Diagnosis The ... to bolus these values ... 30mmHg) - Severe anemia ... #Elevation #Differential
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
breathing system valves ... toxicity (→ 3-10) Acidosis ... #Differential # ... #Diagnosis #Management ... #Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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