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hematology disease hemolysis algorithm antibodies associations autoantibodies behcet causes celiac comparison diseases druginduced extravascular intravascular lupus signs sle symptoms syndrome
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Hypophostphatemia Laboratory ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Cold AIHA • PCH ... • MAHA (TTP ... Prosthetic heart valves ... #Causes #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity - A low value ... If the value is ... WBC count and differential ... #Workup #Hematology
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
Commonly Used Diagnostic ... negative predictive value ... Disease #Testing #Laboratory ... #Tests #Diagnosis ... #Workup #Table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
biliary cirrhosis (PBC ... Endomyseal antibody (EMA ... transglutaminase (TTG ... Associations #diseases #diagnosis ... #table #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
pathognomonic laboratory ... Behcet disease) Differential ... Diagnosis: • Genital ... #management #signs ... #symptoms #rheumatology
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