1744 results
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
#PARADIGM-HF #EMPEROR-Reduced
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... Phosphate binders reduce ... the first-line treatments ... hyperparathyroidism which reduces
Thiazide induced Hyponatremia - Pathophysiology
 • Reduced distal delivery
 • Inhibition of the NCC (dilution capcity)-
Thiazide induced ... Pathophysiology • Reduced ... mechanism • Reduced ... #Thiazide #induced
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
EMPEROR-REDUCED
Algorithm for screening/diagnosis and treatment/follow‐up of iron deficiency in patients with chronic heart failure. Hb, haemoglobin;
/diagnosis and treatment ... heart failure with reduced ... #Indications #Treatment
Summary of actions of some Cholinergic Agonists

Bethanechol 
• Used in treatment of urinary retention 
• Binds
Bethanechol • Used in treatment ... Used topically to reduce ... Pilocarpine • Reduces ... as first-line treatments ... been shown to reduce
Treatment of Wilson's Disease
 • D-penicillamine - Chelator, induces cupruria
 • Trientine - Chelator, induces cupruria
Treatment of Wilson's ... Tetrathiomolybdate - Aims to reduce ... Wilsons #Disease #Treatment
Mechanical Cardiac Support Devices Compared
Cannula Size - Insertion Technique - Haemodynarnic Support
IABP:
 • Afterload: Reduced
 •
• Afterload: Reduced ... pre-load: Slightly reduced ... stroke volume: Reduced ... • LV pre-load: Reduced ... PCW pressure: Reduced
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduced DOAC Dosing ... Fibrillation #DOAC #Reduced
Phimosis 
Inability to retract the foreskin - Can be normal up to 3 years old -
after age 4 Treatment ... • Inability to reduce