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algorithm causes elevatedmcv macrocytosis activation disorders eosinophil macrocytic macrophage management mas mcv naildisorders neutropenia normocytic systemic thrombocytopenia thrombocytosis
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Diagnosis Framework ... aciduria, Drugs (e.g ... Diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Toxic Damage (e.g ... Displacement (e.g ... #Diagnosis #Algorithm ... #Causes #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential # ... diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Diagnosis Algorithm ... Iron Deficiency (Eg ... Other • e.g ... #Microcytic #Anemia ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Diagnosis Algorithm ... Hypersplenism • Secondary ... (e.g. ... Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #hematology #secondary
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Diagnosis Neonate ... hypertension and/or drug treatment ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... underlying disease (eg ... • Infection (eg ... with leukopenia, anemia ... #Hematology #Rheumatology
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