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diagnosis differential causes elevatedmcv management rheumatology activation allergy chronic dermatology eosinophilia erythematosus fatigue female hemeonc hemophagocytic hlh infertility lupus lymphohistiocytosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Increased Requirement (e.g ... Myelodysplastic Syndromes ... Macrocytosis, ... #Macrocytosis # ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Differential Diagnosis Algorithm ... Iron Deficiency (Eg ... Other • e.g ... #Macrocytosis # ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Differential Diagnosis Algorithm ... B-cell lymphomas), Systemic ... mastocytosis, Langerhans ... inflammatory disease: e.g ... Differential #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Differential Diagnosis Algorithm ... Neoplastic / Hematologic ... • Anemia • ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia
Causes of Female Infertility - Differential Diagnosis Algorithm Uterus - HSG or SHG or hysteroscopy: • Fibroids/polyps
Differential Diagnosis Algorithm ... /psychosis • Systemic ... Hyperprolactinemia • Tumors (e.g ... Differential #Diagnosis #Algorithm ... Causes #Obstetrics #OBGyn
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... ▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
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