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diagnosis management rheumatology erythematosus neurology signs sle systemic treatment activation classification cns cryoglobulinemia cryoglobulins hemeonc hemophagocytic hlh lymphohistiocytosis macrophage manifestations
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebritis: Labs ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... disorders (Systemic lupus ... diagnosis #neurology #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... : • Symptoms limited
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... Diagnosis #Management #Hematology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Guillain-Barré syndrome ... GBS), systemic lupus ... IU/I • SAMS clinical ... (SAMS-CI) • EMG
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... : • Clinical triad ... tissue disorder (e.g ... . systemic lupus ... classification #rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... of diagnosis (e.g ... skin (16-32%): lupus ... : (distinct symptoms ... ) • Löfgren syndrome
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... Clinical Presentation ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
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