26 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Megaloblastic Anemia ... (e.g. ... #Peripheral #Blood ... Smear #Analysis #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology ... #secondary
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Iron Deficiency (Eg ... Causes: Chronic Blood ... Secondary to Inflammation ... Other • e.g ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Hypersplenism • Secondary ... (e.g. ... #Normocytic #Anemia ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... infiltration (e.g ... Marrow suppression (e.g ... Intrinsic RBC defects (e.g ... Production #Index #hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #dermatology #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... count, D-dimer, egg ... #Hematology #Pathology