11 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... Microcytic ( ... Infections Macrocytic ... aciduria, Drugs (e.g ... Differential #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
- "Microcytic" ... disease, Acute blood ... - "Macrocytic" ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... Algorithm Normal Blood ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(cell) volume (MCV ... in peripheral blood ... High in acute blood ... of substrate (e.g ... Diagnosis #Workup #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Iron Deficiency (Eg ... Causes: Chronic Blood ... Other • e.g ... #Microcytic #Anemia ... Algorithm #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... • Secondary (e.g ... Polychromatic Macrocytes ... Polychromatic Macrocytes ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... (sometimes) Macrocytic ... Chemotherapy (e.g ... disease, McLeod blood ... differential #diagnosis #hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... function test, ANA (e.g ... anemia (vegan, ... or if a primary hematologic ... Causes #Workup #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... • Infection (eg ... with leukopenia, anemia ... Diagnosis #Management #Hematology ... #Rheumatology