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diagnosis differential rheumatology neurology causes algorithm anemia barre dermatology erythematosus guillain hemolytic hepatology lupus pulmonary sle syndromes systemic thrombocytopenia achalasia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Foreign Surface (e.g
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune ... #treatment #hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute infection ... inflammatory disorders (e.g ... . autoimmune, TB ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... Steroids - 1-2 mg/kg ... Polyclonal: - Infection ... #management #hematology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
an underlying autoimmune ... diagnosis and treatment ... • Enteroviral infections ... • Herpes virus infections ... skull neoplasms (e.g
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Malignancy Infectious ... Hepatitis • HIV Autoimmune ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: HCV infection, ... • Autoimmune diseases ... Often Secondary to Autoimmune ... tissue disorder (e.g ... classification #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis is an autoimmune ... Hodgkin lymphoma - Autoimmune ... Serologic and EMG ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
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