12 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... • Intrinsic RBC ... deficiencies (e.g
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Algorithm Normal Blood ... Neutrophils - Low RBC ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
intake) • Target blood ... Insufficient blood ... Special cases (e.g ... pharmacology #levels #lupus ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... vein thrombosis Hematologic ... titers > 1:80 • CBC
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Volume Reduced RBC ... • Washed RBC ... Transfusions #diagnosis #management ... #hematology #reactions
Management of Convulsive Status Epilepticus in children
Stabilization Phase (Seizure 0-5 minutes):
 • Check and maintain ABC
Management of Convulsive ... • Check blood ... electrolytes, blood ... Epilepticus #seizure #Management ... #neurology #pediatrics
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology