19 results
diagnosis differential causes rheumatology algorithm management systemic thrombocytopenia workup activation analysis arthritis associations atlas autoantibodies autoimmune blood bloodcell chronic classification
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... #diagnosis #table ... antibodies
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Increased Requirement (e.g ... B12 - Anti-IF Antibodies ... B12 - Anti-IF Antibodies ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... (e.g. ... cells: Sickle cell disease ... Smear #Analysis #hematology ... #microscopy #interpretation
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... anemia (sometimes ... Chemotherapy (e.g ... differential #diagnosis #hematology ... #microscopy #atlas
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
secondary to Systemic Diseases ... Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... Systemic #Secondary #dermatology
Urine Microscopy Crystals Uric Acid crystals: - Formation promoted by acidic urine - Seen in tumor lysis
Urine Microscopy ... in tumor lysis syndrome ... specific systemic disease ... urease-producing organisms (e.g ... Crystals #comparison #table
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
PT, aPTT(liver disease ... function test, ANA (e.g ... anti-phospholipid antibodies ... changes), high MCV anemia ... bypass), LFT (liver disease
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Obstructive Pulmonary Disease ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
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