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diagnosis rheumatology lupus management systemic autoantibodies differential activation ana antibodies antinuclear arthritis associations bcnie bloodculture causes cerebritis classification cns comparison
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Clinical Features
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
(SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... (eg, systemic juvenile ... [SLE], AOSD) • ... Infection (eg, ... Diagnosis #Management #Hematology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... is clinically suspected ... overlap syndromes ... Systemic #lupus #erythematosus ... #table #ANA
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Systemic Lupus Erythematosus ... Evolution: Chronic disease ... #comparison #table ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... : - 10% SLE or ... tissue disorder (e.g ... systemic lupus erythematosus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... (e.g., polymyalgia ... Chemistry profile (e.g ... ANA and RF (if clinical
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
risk factors (eg ... hypertension (eg ... 109 mm Hg) with clinical ... hypertension (eg ... Renal parenchymal disease
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... See charts - ... antiphospholipid syndrome ... special stains (e.g ... exists Infectious Diseases
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