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diagnosis hematology differential treatment sle causes criticalcare erythematosus pharmacology systemic acquired activation algorithm anemia antibodies associations autoantibodies blood bloodbank cardiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... diseases #diagnosis #table ... #rheumatology #
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Special cases (e.g ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Hypermagnesemia - Etiologies by Mechanism Renal Failure Excessive Mg Administration - Massive PO intake
IV Mg infusion (e.g ... - Tumor lysis syndrome ... High #Magnesium #Table ... #Causes #Management
Pancreatitis management checklist Evaluation to guide etiology & management - RUQ ultrasound - Calcium
septic shock (e.g ... resuscitation (e.g ... abdominal compartment syndrome ... choledolithiasis (e.g ... limit them as able
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... Shrinking lung syndrome ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... 20% Sjögren's syndrome ... tissue disorder (e.g ... . systemic lupus ... classification #rheumatology
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