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diagnosis rheumatology neurology differential erythematosus management systemic activation acute aki algorithm causes cerebritis cryoglobulinemia cryoglobulins headache hematology kidneyinjury macrophage manifestations
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... Lumbar Puncture, EEG ... #CNS #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... facial numbness), Encephalopathy ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... disorders (Systemic lupus
Common causes of Acute Kidney Injury AKI - Differential Diagnosis HEMODYNAMIC • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... Post-infectious GN, Lupus ... AIN) • Drugs (e.g ... Differential #Diagnosis #nephrology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... • Malignancy (e.g ... Endocrine disorders (e.g ... and CNS • Headache
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... symptoms and signs (e.g ... • Hypertensive encephalopathy ... brain lesion • CNS ... infection (e.g.
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... underlying disease (eg ... SJIA], systemic lupus ... erythematosus [SLE ... • Infection (eg
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... tissue disorder (e.g ... . systemic lupus ... erythematosus (SLE ... diagnosis #types #classification
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