14 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... Lumbar Puncture, EEG ... #CNS #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... facial numbness), Encephalopathy ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... autoimmune disorders (Systemic
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... May be 10 (eg direct ... damage from systemic ... #Classification ... #Proteinuria #Nephrology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... pupil (AACG) • Systemic ... symptoms and signs (e.g ... brain lesion • CNS ... infection (e.g.
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
CNS: parietal ... lobe • Retina • Systemic ... • Infection (e.g ... Brain lesions (e.g ... #diagnosis #neurology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
vasoconstriction (e.g ... inhibitors, hepatorenal syndrome ... : Due to systemic ... AIN) • Drugs (e.g ... Differential #Diagnosis #nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... (CNS) dysfunction ... underlying disease (eg ... erythematosus [SLE ... • Infection (eg
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
central nervous system ... (CNS) involvement ... skull neoplasms (e.g ... leukoencephalopathy and systemic ... #neurology #noninflammatory
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... • Malignancy (e.g ... Endocrine disorders (e.g ... and CNS • Headache
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... tissue disorder (e.g ... . systemic lupus ... erythematosus (SLE ... diagnosis #types #classification