9 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... May be 10 (eg direct ... damage from systemic ... #Classification ... #Proteinuria #Nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Syndrome (MAS) ... (eg, systemic juvenile ... erythematosus [SLE ... • Infection (eg
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... • Malignancy (e.g ... Endocrine disorders (e.g ... Chronic B-cell activation
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Leukemia • MPN/MDS ... B-cell lymphomas), Systemic ... , Behcet disease ... , Sarcoidosis, SLE ... : e.g.
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... #CNS #neurology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Autoimmune diseases ... : - 10% SLE or ... tissue disorder (e.g ... diagnosis #types #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... presentations and disease ... of Circulatory System ... - Compartment syndrome
Indications for Head CT before LP:
 • Age > 60
 • Immunocompromise (e.g., HIV)
 • History
Immunocompromise (e.g ... central nervous system ... (CNS) disease ... risk of having a mass ... #Indications #neurology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
• Autoimmune (SLE ... Vascular: • Systemic ... Cholesterol emboli syndrome ... occlusion that may ... ↑ ESR, CRP • EKG