12 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... Algorithm Cervical ... , Mediastinum, Lungs ... #Algorithm #Causes ... #Hematology #Oncology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... cell disease Rheumatology ... discrepancy, multiple joint ... #Limping #NWB #Algorithm ... Peds #Pediatrics #Diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... • Interstitial lung ... • Shrinking lung ... #pain #differential ... #diagnosis #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
effusions, weight gain ... common • Imaging: CXR ... - pulmonary opacities ... #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... , fever, joint pain ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
vesicular eruption • Joints ... tract, and often causes ... Palpable purpura, joint ... involvement, abdominal pain ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... tract, and often causes ... vesicular eruption - Joints ... , testes -> pain ... #rheumatology #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... classification #hematology ... #oncology #management
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Algorithm in Cancer ... tumors, brain or lung ... chemotherapy, nausea ... , pain) • Cortisol ... #nephrology #oncology