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differential signs systemic erythematosus pain sle management ra rheumatoid testing vasculitis workup ana antibodies antinuclear associations autoantibodies autoimmune bone causes
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... Juvenile Idiopathic Arthritis ... , Interstitial Pulmonary ... #rheumatology # ... diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... #differential #diagnosis ... #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... RA: rheumatoid arthritis ... SLE : systemic lupus ... Comparison #Table #Pulmonary ... #Rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - Arthritis ... Myositis 4% - Lung ... sclerosis, Still's disease ... autoantibodies #signs #symptoms ... #differential #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... • Is there a pattern ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... : • Joint pain ... arthropathy • 90% joints ... : • Symptoms limited ... #Rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Musculoskeletal: Joint ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... disease), PAH ( ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
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