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management signs differential sle systemic comparison hematology table arthritis rheumatoid syndrome testing vasculitis workup abscess activation ana antibodies antinuclear antinxp2
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... effusion, Restrictive lung ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Arthritis: • Joint ... arthropathy • 90% joints ... : • Symptoms limited ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... #Erythematosus ... #signs #symptoms ... #differential #rheumatology
Lung Abscess Microbiology: • Polymicrobial • Anaerobes (most common) Clinical: • Indolent symptoms that evolve
• Indolent symptoms ... , hemoptysis Treatment ... #Abscess #Diagnosis ... #Pulmonary #Clinical ... #CXR #ChestXRay
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus ( ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Treatment: ... Erythematosus ( ... comparison #table #rheumatology ... #diagnosis #management
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... rash) • Heart, lung ... erythematosus [ ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism In contrast to the
Infarction and Pulmonary ... associated with rheumatologic ... erythematosus. ... #Pericarditis #Symptoms ... comparison #Table #Diagnosis
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 Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... common • Imaging: CXR ... - pulmonary opacities ... >3 symptoms, or> ... Renal Failure Treatment
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