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differential oncology hematology infectiousdiseases management contusion ctchest differentiation emergencies extrarticular fungal hemeonc leukemia mycobacteria mycoses nontuberculous ntm oncologic radiology syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... common • Imaging: CXR ... - pulmonary opacities ... : Infection (sepsis ... ), PE, DAH, CHF,
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Extra-articular and Other Conditions ... Pain Eyes ... • Interstitial lung ... #joint #pain #differential ... #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... , fever, joint pain ... manifestations, hypoxia, CXR ... smear: Blasts APML ... #Oncology #Diagnosis
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
massiliense in CF ... • Predisposing conditions ... diarrhea, abdominal pain ... Diagnosis Of NTM ... #differential #diagnosis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... muscle aches, joint ... pain, chest pain ... change in the lungs ... nails, bronchi, lungs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
or as primary condition ... vesicular eruption • Joints ... Palpable purpura, joint ... involvement, abdominal pain ... #Rheumatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
abdomen if abdominal pain ... ; full infectious ... work-up - If febrile ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
breath and chest pain ... located chest pain ... conditions that ... a chest x-ray (CXR ... not seen on a CXR
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