16 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... Calcium oxalate Infectious ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
- pulmonary opacities ... >3 symptoms, or> ... : Infection (sepsis ... ), PE, DAH, CHF, ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : Age>60, CKD, CHF ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... • Interstitial lung ... • Shrinking lung ... #differential #diagnosis ... #rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
massiliense in CF ... Hematologic malignancy ... gastrointestinal symptoms ... Diagnosis Of NTM ... • Clinical (Symptoms
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... Malignancy • Infections ... thrombophlebitis, pulmonary ... #rheumatology # ... hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... bone pain, fever, joint ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Arthritis - Signs and Symptoms ... Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Musculoskeletal: Joint ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... vesicular eruption • Joints ... • Progressive symptoms ... Palpable purpura, joint ... #Rheumatology