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differential signs management systemic arthritis erythematosus lupus pain pathophysiology ra sle approach classification conditions extraarticular extrarticular fungal infections infectiousdiseases mycoses
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... progressing GN • New pulmonary ... vesicular eruption - Joints ... Presentation - Systemic Symptoms ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... effusion, Restrictive lung ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... of Joint Disease ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , Vasculitis (e.g ... #differential #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... vesicular eruption • Joints ... • Progressive symptoms ... Palpable purpura, joint ... #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Vascular: Rheumatoid vasculitis ... Musculoskeletal: Joint ... #diagnosis #rheumatology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... pleural effusion on CXR ... disease/pulmonary ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... life-threatening diseases ... mononeuritis multiplex WORKUP ... or serologies + symptoms ... sparing of the lung
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees) • Incr Axial rotation of thoracic
Exertion, Restrictive Pulmonary ... Disease, Right ... pathophysiology #msk ... #diagnosis #signs ... #symptoms
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