12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... myalgias, HoTN, edema ... Imaging: CXR- pulmonary ... initiation • Differential ... Anaphylaxis, Acute Renal
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... mononeuritis multiplex WORKUP ... #Renal #Syndromes ... diagnosis #management #treatment
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Hypertension - Differential ... ultrasound, Tests ... Duplex Doppler ultrasound ... ; MRA; abdominal ... Causes #Screening #Workup
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Torsemide) • Acute pulmonary ... Postoperative abdominal ... distention • Abdominal ... Tolvaptan) • Treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
, paresthesia, abdominal ... pain, Diffuse edema ... filling +++ (risk of pulmonary ... edema) Treatments ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and renal abnormalities ... - GI tract: abdominal ... Supply gut -> abdominal ... • Urinalysis (Renal ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
CT abdomen if abdominal ... full infectious work-up ... days → add fungal work-up ... , hypotension, renal ... failure, pulmonary
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... multiplex • GI tract: Abdominal ... gut involvement, abdominal ... #Diagnosis #Rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
importantly, bedside ultrasound ... with presence of pulmonary ... edema (“B-lines ... acute coronary syndrome ... #diagnosis #differential