11 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... Acid → SIADH - High ... Uric Acid → renal ... #Algorithm #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... (renal potassium ... #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... Extra-renal Losses ... Syndrome • HTN, High ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential Diagnosis ... perspiration Renal ... #Causes #nephrology ... #sodium #high
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
diuresis can be high ... Present (Uosm ≥100): Hypovolemia ... #differential #diagnosis ... #table #sodium ... #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... - Insulin (high ... overdose) - Sodium ... #differential #diagnosis ... #nephrology #Causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... urinary losses: • High ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
: • Hypovolemia ... Syndrome, Chronic Renal ... Differential #Algorithm #diagnosis ... #causes #nephrology ... #sodium #low
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
- Differential Diagnosis ... Dehydration - Loss of sodium ... heat illness → Hypernatremia ... Collapse: • Pathophysiology ... High body temperatures