26 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Rivaroxaban - Apixaban - Edoxaban ... rivaroxaban #apixaban #edoxaban
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
#Rivaroxaban #Edoxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
if CrCl < 50) Edoxaban ... Rivaroxaban #Dabigatran #Edoxaban
Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism

https://www.nejm.org/doi/full/10.1056/NEJMoa1711948

Authors’ Conclusions: “Oral edoxaban was noninferior to subcutaneous dalteparin
Edoxaban for the ... Conclusions: “Oral edoxaban ... was higher with edoxaban ... have been “oral edoxaban ... KirstyChallen #Edoxaban
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#Rivaroxaban #Edoxaban
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
Apixaban, Dabigatran, Edoxaban
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Rivaroxaban, Apixaban, Edoxaban
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... being stronger for edoxaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Betrixaban (Bevyxxa), Edoxaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 80% Renal Edoxaban