29 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential #Diagnosis ... #Management #gastroenterology ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis ... non-essential drug/HDS treatments ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... (>1000): • DILI ... injury) • Ischemic ... #Differential #Diagnosis ... #hepatology #transaminitis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
abnormality vs bone Bili ... Hepatocellular injury ... 2: Cholestatic injury ... Transaminitis #diagnosis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... • Iatrogenic: DILI ... #differential #diagnosis ... #algorithm #hepatology
RADIAL HEAD FRACTURE 
Radial head fractures are the most common elbow fracture in adults and are
fracture • ED Management ... Splint: Sling • Ortho ... Type I, DC with ortho ... #Radiology #XRay ... #Diagnosis #Management
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... • Acute kidney injury ... #Indications #Management ... #Cirrhosis #treatment ... #hepatology
Posterior Elbow Dislocation
The elbow is the second most commonly dislocated major joint in adults and the
), ligamentous injury ... brachial artery injury ... Simple, DC with ortho ... Dislocation #Posterior #Radiology ... #XRay #Diagnosis
Supracondylar Elbow Fracture
• Most common elbow fracture in children, peak age 5-7 
• When looking at
brachial artery injury ... syndrome • ED Management ... Type l, DC with ortho ... #Humerus #Radiology ... #XRay #Diagnosis