83 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... : - Acute poststreptococcal ... Minimal change disease ... Classification #Nephrology ... Recommended Text: Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Glomerular #Diseases ... #Proteinuria #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Nephritic #Nephrotic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... - Insidious vs Acute ... - Nephritic (hypertension ... #Glomerular #Diseases ... differential #diagnosis #nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... are seen in acute ... Advanced kidney disease ... tubulointerstitial nephritis
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... tubular cells - Acute ... brown cast” - Necrotic ... protein indicating acute ... key #diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... • Interstitial nephritis ... cardiac imaging #Acute ... #causes
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... sodium retention, Urine ... • AKI/CKD • Nephrotic ... Oncotic Pressure • Nephrotic ... • Sepsis • Acute
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... chronic kidney diseases ... suggestive of nephrotic
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... WBCs, or urine ... → Urine culture ... proteinuria, RBC casts ... if cause not identified