30 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Syndrome (CAS): ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... Consumption Disorders ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... Consumption Disorders ... #Hematology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... Diagnosis Algorithm ... of hair, eyes, skin ... McCune Albright syndrome ... #skin #dermatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... symptoms (eg, skin ... #Algorithm #Differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold agglutinins ... Consider RBC membrane disorder ... #workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... #Diagnosis #hematology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... 1) Clinical diagnosis ... Aphaso-apraxo-agnosia syndrome ... hallucinations - Movement disorders ... MNCD #Dementia #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . primary cold agglutin ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... #differential # ... diagnosis #dermatology ... #oncology #clinical ... #skin