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diagnosis hepatology management rheumatology liver algorithm causes dermatology lfts transaminitis acute classification table adultonset autoimmune cirrhosis druginduced gastroenterology lactate lupus
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Severe Acute Liver Injury ... Drug-Induced liver injury ... - Wilson disease ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Elevated Transaminases ... Transaminitis - Differential ... Metabolic: Wilson Disease ... #Differential # ... Diagnosis #causes #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - Differential ... Chronic Viral Hepatitis ... Drug-induced liver injury ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... normal - Hemolysis, NASH ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Sophia_Hayes_MD #Liver #Injury ... #Differential # ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... specificity to elevated ... : > 2 • NASH, ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... fraction < 20% Differential ... hepatomegaly, hepatitis ... diagnosis #management #treatment ... #rheumatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... • Legionnaires disease ... Hepatocellular Injury ... or particular disease ... #differential #
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
specificity to elevated ... of cholestatic disease ... Alcoholic liver disease ... : > 2 • NASH, ... chemistry #diagnosis #differential
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