5 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
HELLP (Hemolysis, Elevated ... * Variant of pre-eclampsia ... AFLP #Obstetrics #OBGyn ... #Hematology #Diagnosis ... #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP (Hemolysis, Elevated ... * Variant of pre-eclampsia ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential # ... diagnosis #icp #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... infiltration) Differential ... Diagnosis: Viral ... #hepatology #obstetrics ... #obgyn #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
if WBC > 5 or elevated ... initiation • Differential ... Diagnosis: Infection ... (sepsis), PE, DAH ... #management #hematology