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diagnosis rheumatology treatment differential disease aflp algorithm hellp hlh lymphohistiocytosis obstetrics pregnancy thrombocytopenia cppd dermatology erythematosus gout hepatology lupus myopathy
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease CDC Case Definition for MIS-C; • < 21
Multi-System Inflammatory ... Syndrome in Children ... disease • Positive COVID ... MISC #Kawasaki #Comparison ... #Syndrome #Children
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Antisynthetase Syndrome ... Idiopathic #Myopathy #Comparison ... #Managment #algorithm ... #Rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
A subset of hemophagocytic ... background of a highly inflammatory ... release of pro-inflammatory ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Overwhelming clinical syndrome ... >500 ng/mL • Elevated ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Genital Lesions - Differential Diagnosis Algorithm Elevated - Vesicles: • Herpes simplex Elevated - Papules / Plaques -
Herpes simplex Elevated ... ) • Reiter's syndrome ... Non-infectious - Inflammatory ... ) • Behcet's syndrome ... #skinlesions #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... → Refer to hematology ... • Nonmalignant hematologic ... myelosuppressive agents • Inflammatory ... Kawasaki, Nephrotic syndrome
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... HELLP (Hemolysis, Elevated ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... production of pro-inflammatory ... Taar #HLH #Hemophagocytic ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... , Elevated uric ... TLS #diagnosis #management ... #hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... HELLP (Hemolysis, Elevated ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
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